Have a browse at the companies based at The Catalyst Newcastle.
GlycanAge is a game-changing product with a potential for exponential growth, as indicated by current growth rates, which already has traction in the market and adoption by leading figures, scientists and clinicians, who have personally subscribed.
The problems of the 21st century are biological
Longevity (aging population)
Biosecurity (the next pandemic)
Out of the five key problems, GlycanAge is relevant to three; glycans regulate your immune system and inflammatory response at multiple levels. Accelerating GlycanAge (inflammaging) better predicts chronic disease incidence and hospitalisation than clinical biomarkers, as demonstrated by this independent study of 11 different molecular aging clocks. The same glycans are directly correlated with reproductive aging.
Glycans are complex sugar molecules that we produce (not eat!) as a structural component of our proteins (the workhorse of our cells) where the glycans regulate the proteins’ functionality and modes of action.
GlycanAge is strategically and technologically positioned, leading the market several years in advance of any potential competitor, bringing a whole new part of human biology to the consumer and clinic:
– Over two decades of research behind the product
– The largest Human Glycome dataset in the world.
– Dataset spans 150,000 people (some who were follow for over 30 years)
– Published finding in over 100+ scientific papers
– Supported by 15M Euro of non-dilutive grant funding
Just as genetic companies like 23andMe had ‘ancestry’ as a proxy to the market (a new and exciting consumer proposition that generated fervor) GlycanAge leads the field of biological aging, the latest and most exciting new industry in both longevity research and personal longevity.
Unlike our genome, and somewhat like the microbiome, our glycome and GlycanAge is not fixed and will respond to lifestyle change, supplement and pharmacological intervention. Hence the opportunity for repeat testing and recurring revenue models.
GlycanAge is a platform company with multiple disease-specific, emerging prognostic biomarkers that can predict conditions like; menopause, cardiovascular disease, and diabetes up to a decade in advance (IP protected) paving the way for the future of preventive health and longevity.
– There will be 1.2 billion women entering menopause by 2025
– Cardiovascular disease is the number one killer globally
– 88% of Americans are metabolically unhealthy
With these three new biomarkers alone, we are addressing the problems of ⅓ of the global population.
National Institute for Health Research (NIHR) Innovation Observatory are the national medical horizon scanning facility located at Newcastle University and The Catalyst.
Horizon scanning is all in the name: keeping an eye on the future for upcoming change. Understanding future medicines, devices and diagnostics helps shape policy, regulation, approvals and stimulate research activity.
The Innovation Observatory is looking for technologies (Horizon Scanning) that are up to 10 years from being publicly available. The difficulty of course is that not all of these technologies will make it to clinical use. For that reason, they are constantly tracking technologies as they evolve, from patent to patient.
At their core are three activities: Technology Briefings where in they provide briefings on technologies to different public stakeholders, such as those delivering care and research funders stimulating innovation. Use of advanced horizon scanning tools, an advanced online search engine, built by the NIHR Innovation Observatory, that allows rapid navigation of different data sources, such as clinical trials registries and mHealth apps. And finally, patient involvement: where in they are actively promoting the dialog between innovators, policy makers and the public by deploying a national online platform for people to learn and help shape innovation.
The consortium behind Mobilise-D consists of many of the world’s leading scientists, clinicians, and companies on mobility assessment in general and the use of body-worn sensors in particular.
More than 150 professionals from 34 participating universities, hospitals, and industry with the necessary technical, clinical, and regulatory expertise will work together over a five-year period (2019-2024) to reach the common goal of validating health care technology.
The consortium will work closely with regulators and other stakeholders to ensure that the solutions are accepted. In addition, representatives from patient and senior organisations, regulatory bodies, and all other relevant stakeholders will be involved throughout the project by participating in project management, stakeholder boards, and stakeholder events.
Recent years have seen rapid developments in the neuromuscular field and a corresponding surge in interest from the pharmaceutical industry. Promising preclinical results raise the potential for new therapies in the near future. Yet translational research towards therapy development for neuromuscular diseases has faced a number of barriers, for patients, for the biomedical industry, for clinicians and researchers
TREAT-NMD addresses all these areas and their relating issues, uniting the stakeholders in the community and providing an infrastructure that is accelerating research and therapy development, increasing collaboration, improving patient care and helping to support ‘clinical trial readiness’ on an international scale.
TREAT-NMD was initially established as a EU funded ‘network of excellence’ with the remit of ‘reshaping the research environment’ in the neuromuscular field. The network has developed from its European roots to become a global organization bringing together leading specialists, patient groups and industry representatives to ensure preparedness for the trials and therapies of the future while promoting best practice today.
The full promise of IoT will only be achieved when you combine the power of Cloud and Edge Computing: delivering real value that allows businesses to analyze and act on their data with incredible agility and precision, and close to real-time.
At the Edge key challenges related to latency, network bandwidth, reliability, security, and OT heterogeneity cannot be addressed in Cloud-only models – the Edge needs its own answers.
IOTech is in the business of providing those answers. Their Edge software products are built on open technology as used by thousands of users worldwide. The products allow you to develop, deploy and manage any AI workloads, third-party Edge applications, or your own business logic on any Internet of Things (IoT) edge node with complete deployment flexibility. Their software solutions cover the full spectrum of secure hard and soft real-time Edge Computing, maximize user choice and provide a software foundation for effective collaboration across multiple vertical markets at the IoT Edge.
Edge Computing will power the next wave of business transformation and there is a unique set of requirements for it. The time to start is now. Avoid the risk of getting left behind, talk to IOTech: The Edge Software Company.
Red Hat are the world’s leading provider of enterprise open source solutions, using a community-powered approach to deliver high-performing Linux, cloud, container, and Kubernetes technologies. They help you standardize across environments, develop cloud-native applications, and integrate, automate, secure, and manage complex environments with award-winning support, training, and consulting services.
They revolutionized the operating system with Red Hat® Enterprise Linux®. Now, they have a broad portfolio, including hybrid cloud infrastructure, middleware, agile integration, cloud-native application development, and management and automation solutions.
Red Hat delivers hardened, open source solutions that make it easier for enterprises to work across platforms and environments, from the core datacenter to the network edge. By operating transparently and responsibly, they continue to be a catalyst in open source communities, helping you build flexible, powerful IT infrastructure solutions.
NICA are the UK’s National Innovation Centre for Ageing – a world-leading organisation supported by an initial investment from UK Government and Newcastle University – to help co-develop and bring to market products and services which create a world in which we all live better, for longer.
They bring together cross-competence professionals and researchers, commercialisation experts, scientists, innovators, and technologists working closely together with the public in a seamless way, exchanging their intelligence.
Their sister organisation VOICE® – Valuing Our Intellectual Capital & Experience – is an international network of thousands of ‘innovation savvy citizens’. Through VOICE®‘s engagement they want to inspire new thinking, and build knowledge and connections to empower people.
Together with VOICE® they have developed a novel approach, Ageing Intelligence®, which leverages the experience, wisdom, skills, insights and expertise of citizens, older adults alongside people of all ages and backgrounds, together with their stakeholders, while harnessing big data.
Their role as a Global Observatory allows them to be uniquely positioned to help enterprises to capitalise on their return-on-society and return-on-business in the longevity economies, generating new thinking and actions.
Using anonymised information gathered as people use our services, ADL Smartcare provide insight to organisations on how people in their locality are ageing, what needs they have, the impact of the services, activities and products that people are using and where there might be gaps.
Organisations can plan their services and see the impact they and their community assets/third sector partners are having on the local population. The insight also gives an organisation information about the numbers of people that they are helping and how they are performing against other areas.
NICRE collaborate, research and co-design ideas to develop innovative solutions. These solutions will foster rural enterprise and unlock the potential of rural economies.
They fill gaps in our current knowledge of rural enterprise and innovation. They achieve this by undertaking and commissioning new research.
NICRE develop practical solutions with businesses, rural communities and economic development agencies. They show new approaches to rural innovation that they can scale up to solve problems and realise new opportunities. They also provide evidence to influence better policy and support for rural businesses.
More than just research, NICRE will aim to make a practical difference. It will achieve this by helping to overturn barriers to rural productivity and seize opportunities, by supporting and championing innovation and enterprise in rural areas and tackling society’s grand challenges and fostering resilient and sustainable rural economies
Their CEO and founder Professor Mike Trenell, has published over 100 peer reviewed academic papers, established collaborations with leading academic institutions and research bodies around the world. This has led to IP and licenses enabling Changing Health to set a new standard in digital therapeutics.
Changing Health is able to provide en masse highly personal and relevant evidence based education and lifestyle coaching, leading to cost effective scale, with a sustained positive impact. Driven by their own artificial intelligence (AI) engine, users can receive education and support based on their needs and preferences.
Delivered via lifestyle coaches, or the platform’s AI. Each user receives a personal experience based on their own goals and background. This ensures the behaviour change intervention creates a lasting impact.
From tracking a user’s movement, to randomised clinical trials. Changing Health is focused on showing the real world impact of it’s services.
Using their discovery platform Hexis Pro.X, they can help you validate and optimise your existing skin product formulations. By identifying new bioactivity and indications, they provide you with the scientific backing for novel marketing claims. You may find that your product has skincare benefits that you didn’t know existed.
Your existing skincare products may possess benefits that you don’t yet know about. If these benefits can be identified and validated, your skincare product will acquire new claims for marketing purposes, helping validate and expand your market share. Their proprietary technology provides new screening capabilities to assess the impact of product ingredients on the systems within skin. This method identifies skin benefits that standard research methods are likely to miss.
They provide a number of bespoke screening services for your bioactive compounds and formulations.
Their team is based at Newcastle University, with offices at the new Catalyst Building in the Helix development in Newcastle upon Tyne and laboratory facilities in the Medical School.
Professor Mark Birch-Machin’s group has pioneered research into mitochondria’s role in skin ageing since 1995. In this time, Mark has had a keen interest in the role lifestyle stress play in mitochondrial dysfunction in skin. His research group is specifically focused on the role sun light, pollution, sleep, and genetic mitochondrial dysfunction have on the skin. For the last 15 years they have been developing the technology behind the Skin Life Test.
Their simple skin swab technique allows you to take samples from different body regions at home or in a clinic. They can test for overall mitochondrial DNA damage in the skin or look at sun specific DNA damage markers in the mitochondria. Their mitochondrial DNA damage technology can help you assess sun damage and track skin interventions. They are focused on developing their technology for applications in personal skincare, clinical dermatology, and research and development. Overall, they can help you make informed and personalised decisions about your skin.
IT@Spectrum is an award-winning technology business with over 35 years’ experience and a track record of helping organisations make significant savings in time and money by introducing highly-efficient, automated business management and print processes.
Quite simply, they put organisations in full control of their printing, documents and information, enabling them to automate systems and processes to improve efficiency – saving both time and money and helping them to focus on what matters most.
Such is the reputation of IT@Spectrum’s work and success, the expertise of their teams is now called upon by leading organisations across the UK. It is their mission to ensure each solution they implement is bespoke to the customer and improves efficiency and productivity, whilst decreasing operating costs.
Jumping Rivers is an analytics company whose passion is data and machine learning. We help our clients move from data storage to data insights.
Jumping Rivers has delivered quality data insights from day 1. Based in Newcastle and founded in 2016, the company is bringing a fresh approach to the world of data analytics. Our trainers and consultants come with over 40 years combined experience in R, Python, Stan, Scala and other programming languages. We have worked with some of the largest (and smallest) companies in the world.
DTG is a Digital Transformation company, delivering technology and solutions that enable clients to embrace the operational, cultural and financial benefits of digitalisation with automated technologies.
We deliver a unique combination of technical, knowledge, practical experience, vendor relationships, proprietary technology & tools and delivery mechanism that supports clients from initial concept & business planning through to implementation and life-cycle management.
We bring ideas to solutions – Transforming Manufacturing Productivity through an Enhanced Digitalisation Strategy.
The National Innovation Centre for Data (NICD) is playing a leading role in addressing the shortage of data analytics skills in the UK through a new ground breaking facility designed to encourage and create a vibrant eco-system around data science.
Engaging with NICD enables organisations to gain insight from their data, allowing them to optimise existing operations and to grow by launching new products and services.
Their flexible rolling programme of collaborative projects with clients, focused on their specific business challenges and opportunities, is transferring practical data skills into the workforce of private and public sector organisations across the UK.
AkzoNobel are experts in the proud craft of making paints and coating, setting the standard in colour and protections since 1792. Portfolio of brands include Dulex, International, Sikkens and Interpon.
They’ve been pioneering a world of possibilities to bring surfaces to life for well over 200 years. As experts in making coatings, there’s a good chance you’re only ever a few meters away from one of their products.
Their world class portfolio of brands – including Dulux, International, Sikkens and Interpon – is trusted by customers around the globe. They’re active in more than 150 countries and have set their sights on becoming the global industry leader. It’s what you’d expect from the most sustainable paints company, which has been inventing the future for more than two centuries.
Their vision is to champion change and to constantly look to the future. To transform the way people recruit, to change the way people learn and to positively shift perception of apprenticeships. Ultimately, they change lives.
Baltic’s specialist apprenticeship programmes launch careers in IT, software development and digital marketing. They are the first training provider to offer a completely digital apprenticeship training platform. They are passionate in making a recognised social impact.
They are dedicated, digital experts who are passionate about making a recognised social impact. Regardless of race, gender, location and economic status, their innovative approach to technical training is bringing a host of opportunities to those who may have previously considered a career in tech to be out of reach.
Urban Foresight® was established in 2011 as the world’s first dedicated smart city consultancy. They are on a mission driven business that thinks deeply about the opportunities to transform services and solve societal challenges. Their multi-disciplinary team works across different sectors and is skilled at translating ideas into action.
They provide technical and commercial support to help their clients develop new technologies and services for cities. This includes writing award winning reports, providing evidence-based insights and delivering investment-ready strategies.
Urban Foresight also provides the resource, expertise and funding to deliver innovations. Their team helps cities to procure innovation, manage innovation pilots and deliver smart city programmes. They also help businesses to create opportunities to commercialise and scale-up new innovations.
Urban Foresight’s partners benefit from their expertise in funding, financing and accessing new markets around the world. They have a proud track record of securing millions of pounds of investment in infrastructure and advanced urban services.